Article

Bone Morphogenetic Protein signaling pathway – ethanol interactions disrupt palate formation independent of <i>gata3</i>

2024-11-15

Abstract excerpt

Fetal Alcohol Spectrum Disorders (FASD) describes a wide array of neurological defects and craniofacial malformations, associated with ethanol teratogenicity. While there is growing evidence for a genetic component to FASD, little is known of the genes underlying these ethanol-induced defects. Along with timing and dosage, genetic predispositions may help explain the variability within FASD. From a screen for gene...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fb643381-e963-5fda-8646-3db8a02226b6
DOI: 10.1101/2024.11.15.623833

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bone Morphogenetic Protein signaling pathway – ethanol interactions disrupt palate formation independent of <i>gata3</i>DOI 10.1101/2024.11.15.623833Read

Bone morphogenetic protein signaling pathway- Ethanol interactions disrupt palate formation independent of gata3.Semantic proximity Read

Mutations in the Bone Morphogenetic Protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformationsSemantic proximity Read

Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD.Semantic proximity Read

A screen of zebrafish mutants identifies ethanol-sensitive genetic loci.Semantic proximity Read

Xenopus embryos to study fetal alcohol syndrome, a model for environmental teratogenesisSemantic proximity Read

Variation in phenotypes from a Bmp-Gata3 genetic pathway is modulated by Shh signaling.Semantic proximity Read

Gene-environment interactions characterized by single embryo transcriptomicsSemantic proximity Read

Fishing for Fetal Alcohol Spectrum Disorders: Zebrafish as a Model for Ethanol TeratogenesisSemantic proximity Read

Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathwaySemantic proximity Read

Zebrafish models of fetal alcohol spectrum disordersSemantic proximity Read

Zebrafish as a Model for Fetal Alcohol Spectrum DisordersSemantic proximity Read

Embryonic ethanol exposure alters expression of sox2 and other early transcripts in zebrafish, producing gastrulation defectsSemantic proximity Read