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Article

Phenotypic variability and craniofacial dysmorphology: increased shape variance in a mouse model for cleft lip.

Journal of anatomy - 1 Feb 2008

Parsons Trish E, Kristensen Erika, Hornung Lynnette, Diewert Virginia M, Boyd Steven K, German Rebecca Z, Hallgrímsson Benedikt

Abstract excerpt

Cleft lip and palate (CL/P), as is true of many craniofacial malformations in humans, is etiologically complex and highly variable in expression. A/WySn mice are an intriguing model for human CL/P because they develop this dysmorphology with a variable expression pattern, incomplete penetrance and frequent unilateral expression on a homogeneous genetic background. The developmental basis for this variation in...

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Identifiers

PMID: 18093101
DOI: 10.1111/j.1469-7580.2007.00845.x
PMCID: PMC2408978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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