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Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation

23 Dec 2021

Abstract excerpt

Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events. However, it remains unclear which cells in tendons can respond to IL-17A, and how IL-17A, and its family members IL-17F and IL-17AF, can affect intracellular signalling activation...

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PMID: 35004653
DOI: 10.3389/fbioe.2021.795830

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