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Article

Gene Expression Profiling of IL‐17A‐Treated Synovial Fibroblasts from the Human Temporomandibular Joint

1 Jan 2015

Abstract excerpt

Synovial fibroblasts contribute to the inflammatory temporomandibular joint under pathogenic stimuli. Synovial fibroblasts and T cells participate in the perpetuation of joint inflammation in a mutual activation feedback, via secretion of cytokines and chemokines that stimulate each other. IL-17 is an inflammatory cytokine produced primarily by Th17 cells which plays critical role in the pathogenesis of numerous...

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PMID: 26839464
DOI: 10.1155/2015/436067

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