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Article

IL-21 receptor expression in human tendinopathy.

Mediators of inflammation - 1 Jan 2014

Campbell Abigail L, Smith Nicola C, Reilly James H, Kerr Shauna C, Leach William J, Fazzi Umberto G, Rooney Brian P, Murrell George A C, Millar Neal L

Abstract excerpt

The pathogenetic mechanisms underlying tendinopathy remain unclear, with much debate as to whether inflammation or degradation has the prominent role. Increasing evidence points toward an early inflammatory infiltrate and associated inflammatory cytokine production in human and animal models of tendon disease. The IL-21/IL-21R axis is a proinflammatory cytokine complex that has been associated with chronic...

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Identifiers

PMID: 24757284
DOI: 10.1155/2014/481206
PMCID: PMC3976844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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