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Article

Early atypical malignant transformation of diffuse low-grade astrocytoma: The importance of genotyping.

Neurocirugia (English Edition) - 1 Jan 2000

Valente Aguiar Pedro, Sousa Osvaldo, Silva Roberto, Vaz Rui, Linhares Paulo

Abstract excerpt

Diffuse astrocytoma (WHO grade II) has classically been considered a slow growing tumour, typically affecting young adults, with tendency for late malignant conversion. We describe a case of early atypical malignant transformation of diffuse astrocytoma seventeen months after complete surgical removal, as an intraventricular high-grade glioma (HGG). Retrospective laboratory findings for the presence of IDH 1/2...

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Identifiers

PMID: 34998489
DOI: 10.1016/j.neucie.2020.09.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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