Article
Finding of IDH1 R132H mutation in histologically non-neoplastic glial tissue changes surgical strategies, a case report.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Jul 2017
Søndergaard Christian Baastrup, Scheie David, Sehested Astrid Marie, Skjøth-Rasmussen Jane
Abstract excerpt
INTRODUCTION: In 2016, the WHO classification of diffuse astrocytoma began to include isocitrate dehydrogenase (IDH) mutation in addition to histology. RESULTS: We here demonstrate a case where a 14-year-old boy presented with a parietal tumor with no histological evidence of neoplasia but with an IDH1 mutation. Due to the IDH1 R132H mutation, the patient was diagnosed with diffuse astrocytoma WHO grade II and...
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