Article
Genetic Risk Scores for Type 1 Diabetes Prediction and Diagnosis.
Current diabetes reports - 28 Oct 2017
Redondo Maria J, Oram Richard A, Steck Andrea K
Abstract excerpt
PURPOSE OF REVIEW: About 50% of the heritability of type 1 diabetes (T1D) is attributed to human leukocyte antigen (HLA) alleles and the remainder to several (close to 50) non-HLA loci. A current challenge in the field of the genetics of T1D is to apply the knowledge accumulated in the last 40 years towards differential diagnosis and risk assessment. RECENT FINDINGS: T1D genetic risk scores seek to combine the...
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