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Article

ATM and TP53 polymorphisms modified susceptibility to radiation-induced lens opacity in natural high background radiation area, China.

International journal of radiation biology - 1 Jan 2022

Gao Yu, Su Yin-Ping, Li Xiao-Liang, Lei Shu-Jie, Chen Hui-Feng, Cui Shi-Yue, Zhang Su-Fen, Zou Jian-Ming, Liu Qing-Jie, Sun Quan-Fu

Abstract excerpt

Purpose: A population-based case-control study was conducted in Yangjiang and Enping areas in South China to assess whether the risk of lens opacity induced by natural high background radiation exposure is modulated by polymorphisms of ATM and TP53.Materials and methods: A total of 133 cases who were diagnosed with cortical and posterior subcapsular (PSC) opacity were recruited, and 419 healthy controls were...

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PMID: 34995174
DOI: 10.1080/09553002.2022.2024294

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