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[Study on gene-gene, gene-environmental interactions of DNA repair genes related with age-related cataract].

Zhonghua yi xue za zhi - 22 Apr 2014

Yang Mei, Su Shu, Zhou Jing, Zhu Rongrong, Qin Bai, Yang Ling, Zhang Junfang, Shi Jian, Liang Congkai, Liu Bihong, Qi Yingxiang, Guan Huaijin

Abstract excerpt

OBJECTIVE: To investigate the interaction between polymorphisms and environment factors in age related cataract (ARC). METHODS: Population-based case-control study. All of 448 cataract cases were selected from cataract eye database and 248 controls were recruited from Funing county. All 18 single nucleotide polymorphism (SNPs) of WRN, OGG1, BLM and ERCC6 genes were genotyped using real-time fluorescent...

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Identifiers

PMID: 24924712

Genes

ARC
WRN
BLM
ERCC6
OGG1

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