Article
Gene-environment interaction for polymorphisms in ataxia telangiectasia-mutated gene and radiation exposure in carcinogenesis: results from two literature-based meta-analyses of 27120 participants.
Oncotarget - 22 Nov 2016
Zhao Yuguang, Yang Lei, Wu Di, He Hua, Wang Mengmeng, Ge Tingwen, Liu Yudi, Tian Huimin, Cui Jiuwei, Jia Lin, Wan Ziqiang, Han Fujun
Abstract excerpt
PURPOSE: We conducted two meta-analyses of ATM genetic polymorphisms and cancer risk in individuals with or without radiation exposure to determine whether there was a joint effect between the ATM gene and radiation exposure in carcinogenesis. RESULTS: rs1801516, which was the only ATM polymorphism investigated by more than 3 studies of radiation exposure, was eligible for the present study. The meta-analysis of...
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