Article
On the Nature of Murine Radiation-Induced Subcapsular Cataracts: Optical Coherence Tomography-Based Fine Classification, In Vivo Dynamics and Impact on Visual Acuity.
Radiation research - 1 Jan 2022
Pawliczek Daniel, Fuchs Helmut, Gailus-Durner Valerie, de Angelis Martin Hrabê, Quinlan Roy, Graw Jochen, Dalke Claudia
Abstract excerpt
Ionizing radiation is widely known to induce various kinds of lens cataracts, of which posterior subcapsular cataracts (PSCs) have the highest prevalence. Despite some studies regarding the epidemiology and biology of radiation-induced PSCs, the mechanism underscoring the formation of this type of lesions and their dose dependency remain uncertain. Within the current study, our team investigated the in vivo...
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