Article
Follistatin-related protein 1 interacting partner of Syndecan-1 promotes an aggressive phenotype on Oral Squamous cell carcinoma (OSCC) models.
Journal of proteomics - 15 Mar 2022
Zandonadi Flávia S, Yokoo Sami, Granato Daniela Campos, Rivera César, Macedo Carolina Carneiro Soares, Soares Ciro Dantas, Carnielli Carolina Moretto, Domingues Romênia Ramos, Pauletti Bianca A, Consonni Sílvio Roberto, Colleta Ricardo D, Paes Leme Adriana F
Abstract excerpt
Syndecans belong to the family of transmembrane heparan sulfate proteoglycans and are associated with many physiopathological processes, including oral cancer. As previously shown soluble syndecan-1 (SDC1) fragments and synthetic SDC1 peptide were able to induce cell migration in oral cancer cell lines. In order to explore the role of SDC1 in oral cancer, we have investigated SDC1 interacting partners and its...
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