Article
EEF1D modulates proliferation and epithelial-mesenchymal transition in oral squamous cell carcinoma.
Clinical science (London, England : 1979) - 1 May 2016
Flores Isadora L, Kawahara Rebeca, Miguel Márcia C C, Granato Daniela C, Domingues Romênia R, Macedo Carolina C S, Carnielli Carolina M, Yokoo Sami, Rodrigues Priscila C, Monteiro Bárbara V B, Oliveira Carine E, Salmon Cristiane R, Nociti Francisco H, Lopes Márcio A, Santos-Silva Alan, Winck Flavia V, Coletta Ricardo D, Paes Leme Adriana F
Abstract excerpt
EEF1D (eukaryotic translation elongation factor 1δ) is a subunit of the elongation factor 1 complex of proteins that mediates the elongation process during protein synthesis via enzymatic delivery of aminoacyl-tRNAs to the ribosome. Although the functions of EEF1D in the translation process are recognized, EEF1D expression was found to be unbalanced in tumours. In the present study, we demonstrate the...
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