Article
Expression of Programmed Cell Death 1 and Helios Genes Correlates With rs872071A>G and rs12203592C>T Single-Nucleotide Polymorphisms of InterferonRegulatory Factor 4 in Patients with T-Cell-Mediated Rejection of Renal Allograft.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 Feb 2022
Alamdari Azam, Minoo Farzaneh Sadat, Assadiasl Sara, Freidoon Mahboobeh, Pour-Reza-Gholi Fatemeh, Soleimanifar Narjes, Mohebbi Bahareh, Sadr Maryam, Lesan Pezeshki Mahboob, Nicknam Mohammad Hossein
Abstract excerpt
OBJECTIVES: Acute T-cell-mediated rejection of the renal allograft is a serious posttransplant challenge that requires administration of high-dose immunosuppressive drugs with considerable side effects; therefore, specific targeting of T-cell responses may improve both prevention and treatment of T-cell-mediated rejection. A potential candidate for this purpose is interferon regulatory factor 4 because of its...
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