Article
Genome-Wide Identification of N6-Methyladenosine Associated SNPs as Potential Functional Variants for Type 1 Diabetes.
Frontiers in endocrinology - 1 Jan 2022
Chen Yang, Shen Min, Ji Chen, Huang Yanqian, Shi Yun, Ji Li, Qin Yao, Gu Yong, Fu Qi, Chen Heng, Xu Kuanfeng, Yang Tao
Abstract excerpt
Objectives: N6-methyladenosine (m6A) is essential in the regulation of the immune system, but the role that its single nucleotide polymorphisms (SNPs) play in the pathogenesis of type 1 diabetes (T1D) remains unknown. This study demonstrated the association between genetic variants in m6A regulators and T1D risk based on a case-control study in a Chinese population. Methods: The tagging SNPs in m6A regulators...
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