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Article

Are Fc Gamma Receptor Polymorphisms Important in HIV-1 Infection Outcomes and Latent Reservoir Size?

Frontiers in immunology - 1 Jan 2021

Lamptey Helena, Bonney Evelyn Y, Adu Bright, Kyei George B

Abstract excerpt

Fc gamma receptors (FcγR) are cell surface glycoproteins which trigger specific effector-cell responses when cross-linked with the Fc portions of immunoglobulin (IgG) antibodies. During HIV-1 infection, the course of disease progression, ART response, and viral reservoir size vary in different individuals. Several factors may account for these differences; however, Fc gamma receptor gene polymorphisms, which...

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Share to Antibodies, Neutralizing
Share to Antiretroviral Therapy, Highly Active

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, IgG

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Identifiers

PMID: 34017334
DOI: 10.3389/fimmu.2021.656894
PMCID: PMC8129575

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