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TFEB Biology and Agonists at a Glance

5 Feb 2021

Abstract excerpt

Autophagy is a critical regulator of cellular survival, differentiation, development, and homeostasis, dysregulation of which is associated with diverse diseases including cancer and neurodegenerative diseases. Transcription factor EB (TFEB), a master transcriptional regulator of autophagy and lysosome, can enhance autophagic and lysosomal biogenesis and function. TFEB has attracted a lot of attention owing to...

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PMID: 33562649
DOI: 10.3390/cells10020333

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