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Article

Association between genetic variant rs2267716 of CRHR2 gene with colorectal cancer.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Apr 2022

Ramírez-Guerrero Angélica Araceli, González-Villaseñor Christian Octavio, Leal-Ugarte Evelia, Gutiérrez-Angulo Melva, Ramírez-Flores Mario, Delgado-Enciso Iván, Macías-Gómez Nelly Margarita

Abstract excerpt

Colorectal cancer (CRC) is the third most common cancer and one of the main causes of death around the world. Multiple lines of evidence have suggested the role of the corticotropin-releasing hormone (CRH) family in CRC induction, including the low expression of corticotropin-releasing hormone receptor 2 (CRHR2), which is an angiogenesis inhibitor and inflammatory modulator. Previous research suggests that CRHR2...

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PMID: 34969780
DOI: 10.1136/jim-2021-002047

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