Article
An intronic polymorphism in the corticotropin-releasing hormone receptor 2 gene increases susceptibility to HBV-related hepatocellular carcinoma in Chinese population.
Human genetics - 1 Jan 2010
Gu Xing, Qi Peng, Zhou Feiguo, Ji Qiang, Wang Hao, Dou Tonghai, Zhao Yunpeng, Gao Chunfang
Abstract excerpt
Corticotropin-releasing hormone receptor 2 (CRHR2) plays a role in both the central nervous system (CNS) and the peripheral nervous system. CRHR2 together with its ligands, urocortins (Ucns) and corticotropin-releasing hormone (CRH), functions as a mediator of inflammatory response and inhibitor...
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