Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Association of estrogen receptor beta variants and serum levels of estradiol with risk of colorectal cancer: a case control study.

BMC cancer - 3 Jul 2012

Wu Huanlei, Xu Li, Chen Jigui, Hu Junbo, Yu Shiying, Hu Guangyuan, Huang Liu, Chen Xiaoping, Yuan Xianglin, Li Guojun

Abstract excerpt

BACKGROUND: Endogenous estrogens may play a vital role in colorectal tumorigenesis. Estrogen receptor beta is the predominant subtype which mediates the biological effect of estrogens, while loss of expression of estrogen receptor beta has been indicated as a common step in the development of colorectal cancer (CRC). Epidemiological studies have revealed several functional polymorphisms of estrogen receptor beta...

Topics

Join the communities discussing this publication.

Aged
Case-Control Studies
Colorectal Neoplasms
Estradiol
Estrogen Receptor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 22759347
DOI: 10.1186/1471-2407-12-276
PMCID: PMC3472165

Genes

ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of estrogen receptor beta variants and serum levels of estradiol with risk of colorectal cancer: a case control study.PMID 22759347Read ↗

Association of estrogen receptor-beta (ESR2) polymorphism and cancer risk: a meta-analysis.Semantic proximity Read ↗

Estrogen receptor-β gene polymorphism and colorectal cancer risk: effect modified by body mass index and isoflavone intake.Semantic proximity Read ↗

Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk.Semantic proximity Read ↗

A systematic review of the relationship between polymorphic sites in the estrogen receptor-beta (ESR2) gene and breast cancer risk.Semantic proximity Read ↗

Estrogen Receptors in Colorectal Cancer: Facts, Novelties and PerspectivesSemantic proximity Read ↗

Common single-nucleotide polymorphisms in the estrogen receptor β promoter are associated with colorectal cancer survival in postmenopausal women.Semantic proximity Read ↗

Estrogen receptor beta (ESR2) polymorphisms in familial and sporadic breast cancer.Semantic proximity Read ↗

Colorectal cancer risk associated with hormone use varies by expression of estrogen receptor-β.Semantic proximity Read ↗

Oestrogen receptor-β CA repeat polymorphism is associated with incidence of colorectal cancer among females.Semantic proximity Read ↗

Sex differences in epidemiological, clinical and pathological characteristics of colorectal cancer.Semantic proximity Read ↗

ESR2 gene variants (rs1256049, rs4986938, and rs1256030) and their association with breast cancer risk.Semantic proximity Read ↗

Genetic polymorphisms in the estrogen receptor beta (ESR2) gene and the risk of epithelial ovarian carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.