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Association of CASP8 rs3834129 and CTGF rs6918698 genotypes with susceptibility to colorectal cancer in a Mexican population.

Cellular and molecular biology (Noisy-le-Grand, France) - 27 Nov 2024

Saucedo-Sariñana Anilú Margarita, Trujillo-Fernández Yuri Giovanna Vanessa, Juarez-Vázquez Clara Ibet, Godínez-Rodríguez Miriam Yadira, Tovar-Jácome César de Jesús, Barros-NúñeZ Patricio, Pineda-Razo Tomás Daniel, Marín-Contreras María Eugenia, Rosales-Reynoso Mónica Alejandra

Abstract excerpt

Connective tissue growth factor (CTGF) and Caspase 8 (CASP8) have been implicated in cancer development and progression. Variants such as CASP8 rs3834129 (-652 6N I/D) and CTGF rs6918698 (-945 C>G) have been associated with several cancers, although their association is still debated between populations. This study investigates the possible association between the CASP8 rs3834129 and CTGF rs6918698 variants with...

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PMID: 39707786
DOI: 10.14715/cmb/2024.70.11.2

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