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Article

Dysregulation of vitamin D synthesis pathway genes in colorectal cancer: A case-control study.

Journal of clinical laboratory analysis - 1 Feb 2021

Sadeghi Hossein, Kamaliyan Zeeba, Mohseni Roohollah, Sahebi Unes, Nazemalhosseini-Mojarad Ehsan, Aghaei Naser, Zali Mohammad Reza, Asadzadeh Aghdaei Hamid, Mirfakhraie Reza, Moshiri Arfa

Abstract excerpt

BACKGROUND: The cytochromes P450 are a superfamily of enzymes that control the synthesis of the biologically active form of vitamin D, 1,25-dihydroxyvitamin D3. These enzymes contribute to the formation of 1,25-dihydroxyvitamin D3, which starts with a 25-hydroxylation by CYP2R1 and CYP27A1 and a subsequent 1α-hydroxylation via CYP27B1. METHODS: By using quantitative real-time polymerase chain reaction (qRT-PCR),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33058307
DOI: 10.1002/jcla.23617
PMCID: PMC7891505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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