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Article

APOE4 Allele, Sex, and Dementia Risk in Parkinson's Disease: Lessons From a Longitudinal Cohort.

Journal of geriatric psychiatry and neurology - 1 Nov 2022

Umeh Chizoba C, Mahajan Abhimanyu, Mihailovic Aleksandra, Pontone Gregory M

Abstract excerpt

INTRODUCTION: The effect of APOE4 allele on dementia risk is well established in Alzheimer's disease and Parkinson's disease (PD). However, it is unknown if sex modifies this relationship. We sought to determine the effect of sex on the relationship between APOE4 status and incident cognitive decline in PD. METHODS: Data from the prospectively collected longitudinal National Alzheimer's Coordinating Center (NACC)...

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Identifiers

PMID: 34958617
DOI: 10.1177/08919887211060019
PMCID: PMC11062588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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