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Article

The role of APOE in cognitive trajectories and motor decline in Parkinson's disease.

Scientific reports - 9 Apr 2021

Jo Sungyang, Kim Seon-Ok, Park Kye Won, Lee Seung Hyun, Hwang Yun Su, Chung Sun Ju

Abstract excerpt

We aimed to investigate the role of the APOE genotype in cognitive and motor trajectories in Parkinson's disease (PD). Using PD registry data, we retrospectively investigated a total of 253 patients with PD who underwent the Mini-Mental State Exam (MMSE) two or more times at least 5 years apart, were aged over 40 years, and free of dementia at the time of enrollment. We performed group-based trajectory modeling...

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Identifiers

PMID: 33837234
DOI: 10.1038/s41598-021-86483-w
PMCID: PMC8035327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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