Article
Genomic Characterization of De Novo Metastatic Breast Cancer.
Clinical breast cancer - 1 Feb 2022
Mullangi Samyukta, Vasan Neil
Abstract excerpt
De novo metastatic breast cancer (dnMBC) represents a minority of MBC cases, and as such, its genomics are poorly understood. Characterizing the genomics of dnMBC represents an opportunity to delineate metastatic drivers in the absence of treatment selection. In this review, we first summarize the literature of the genomics of MBC which showed that MBCs have greater mutational burden than early stage, treatment...
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