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Article

Live-Cell Imaging of Single Neurotrophin Receptor Molecules on Human Neurons in Alzheimer's Disease.

International journal of molecular sciences - 9 Dec 2021

Barabás Klaudia, Kobolák Julianna, Godó Soma, Kovács Tamás, Ernszt Dávid, Kecskés Miklós, Varga Csaba, Jánosi Tibor Z, Fujiwara Takahiro, Kusumi Akihiro, Téglási Annamária, Dinnyés András, Ábrahám István M

Abstract excerpt

Neurotrophin receptors such as the tropomyosin receptor kinase A receptor (TrkA) and the low-affinity binding p75 neurotrophin receptor p75NTR play a critical role in neuronal survival and their functions are altered in Alzheimer's disease (AD). Changes in the dynamics of receptors on the plasma membrane are essential to receptor function. However, whether receptor dynamics are affected in different...

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Identifiers

PMID: 34948057
DOI: 10.3390/ijms222413260
PMCID: PMC8708879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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