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Aspects of the Epigenetic Regulation of EMT Related to Cancer Metastasis

6 Dec 2021

Abstract excerpt

Epithelial to mesenchymal transition (EMT) occurs during the pathological process associated with tumor progression and is considered to influence and promote the metastatic cascade. Characterized by loss of cell adhesion and apex base polarity, EMT enhances cell motility and metastasis. The key markers of the epithelial to mesenchymal transition are proteins characteristic of the epithelial phenotype, e.g.,...

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PMID: 34943943
DOI: 10.3390/cells10123435

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