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Article

Epigenetics of epithelial‐to‐mesenchymal transition in pancreatic carcinoma

30 Jan 2017

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant diseases with late diagnosis, rapid progression, high invasiveness, and early metastasis. Epithelial-to-mesenchymal transition (EMT) is a crucial step in metastasis that enables polarized immotile epithelial cells to gain fibroblast-like mesenchymal abilities such as enhanced motility. The dynamic process of EMT in PDAC with its powerful...

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PMID: 28133736
DOI: 10.1002/ijc.30626

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