Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of genetic and microenvironmental factors in cancer epithelial-to-mesenchymal transition and therapeutic implication.

Experimental cell research - 15 Sept 2018

Yang Liuqi, Shang Zhengling, Long Shiqi, Wang Nianxue, Shan Ge, Zhang Ruya

Abstract excerpt

Epithelial-to-mesenchymal transition (EMT) is a process in which epithelial cells lose their cell-cell contacts resulting in the formation of mesenchymal cells with migratory properties. Increasing evidence indicate EMT plays a key role in the invasion, metastasis and therapeutic resistance of cancer and maintenance of the phenotype of cancer stem cells (CSCs), which makes the prognosis of patients worse. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Communication
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

Share to Neoplastic Stem Cells

Share to Phenotype

Share to Tumor Microenvironment

Source

Identifiers

PMID: 30075173
DOI: 10.1016/j.yexcr.2018.07.046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of genetic and microenvironmental factors in cancer epithelial-to-mesenchymal transition and therapeutic implication.PMID 30075173Read ↗

Factors Determining Epithelial-Mesenchymal Transition in Cancer ProgressionSemantic proximity Read ↗

Epithelial–mesenchymal transition in cancer development and its clinical significanceSemantic proximity Read ↗

The Epithelial-Mesenchymal Transition and Cancer Stem Cells: Functional and Mechanistic LinksSemantic proximity Read ↗

Clinical significance of epithelial-mesenchymal transition and cancer stem cells.Semantic proximity Read ↗

The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasisSemantic proximity Read ↗

Deciphering the Dynamics of Epithelial-Mesenchymal Transition and Cancer Stem Cells in Tumor ProgressionSemantic proximity Read ↗

Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells?Semantic proximity Read ↗

Epithelial to Mesenchymal Transition in a Clinical PerspectiveSemantic proximity Read ↗

Molecular regulation of epithelial-to-mesenchymal transition in tumorigenesis (Review)Semantic proximity Read ↗

Concise Review: Stem Cells and Epithelial-Mesenchymal Transition in Cancer: Biological Implications and Therapeutic TargetsSemantic proximity Read ↗

Epithelial Mesenchymal Transition in Aggressive Lung Cancers.Semantic proximity Read ↗

Epithelial-mesenchymal plasticity—engaging stemness in an interplay of phenotypesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.