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Article

A Comprehensive DNA Methylation Profile of Epithelial-to-Mesenchymal Transition

9 Aug 2014

Abstract excerpt

Epithelial-to-mesenchymal transition (EMT) is a plastic process in which fully differentiated epithelial cells are converted into poorly differentiated, migratory and invasive mesenchymal cells, and it has been related to the metastasis potential of tumors. This is a reversible process and cells can also eventually undergo mesenchymal-to-epithelial transition. The existence of a dynamic EMT process suggests the...

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PMID: 25106427
DOI: 10.1158/0008-5472.can-13-3659

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