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Article

The epigenetics of epithelial-mesenchymal plasticity in cancer.

Nature medicine - 1 Nov 2013

Tam Wai Leong, Weinberg Robert A

Abstract excerpt

During the course of malignant cancer progression, neoplastic cells undergo dynamic and reversible transitions between multiple phenotypic states, the extremes of which are defined by the expression of epithelial and mesenchymal phenotypes. This plasticity is enabled by underlying shifts in epigenetic regulation. A small cohort of pleiotropically acting transcription factors is widely recognized to effect these...

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Identifiers

PMID: 24202396
DOI: 10.1038/nm.3336
PMCID: PMC4190672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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