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Article

Epithelial to Mesenchymal Transition in a Clinical Perspective

1 Jan 2015

Abstract excerpt

Tumor growth and metastatic dissemination rely on cellular plasticity. Among the different phenotypes acquired by cancer cells, epithelial to mesenchymal transition (EMT) has been extensively illustrated. Indeed, this transition allows an epithelial polarized cell to acquire a more mesenchymal phenotype with increased mobility and invasiveness. The role of EMT is quite clear during developmental stage. In the...

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Identifiers

PMID: 26425122
DOI: 10.1155/2015/792182

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