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Propagation of TDP-43 proteinopathy in neurodegenerative disorders

11 Dec 2021

Abstract excerpt

Neurodegenerative disorders are characterized by disruptions to neuronal function and circuitry, leading to a variety of clinical syndromes depending on the affected neuroanatomic regions (Geula, 1998). Many proteinopathies implicated in neurodegenerative diseases are characterized by the pathologic accumulation of proteins into inclusions that are initially deposited in specific areas of the brain and spread...

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PMID: 34916432
DOI: 10.4103/1673-5374.330609

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