Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synthetic DNA spike-ins (SDSIs) enable sample tracking and detection of inter-sample contamination in SARS-CoV-2 sequencing workflows

14 Dec 2021

Abstract excerpt

The global spread and continued evolution of SARS-CoV-2 has driven an unprecedented surge in viral genomic surveillance. Amplicon-based sequencing methods provide a sensitive, low-cost and rapid approach but suffer a high potential for contamination, which can undermine laboratory processes and results. This challenge will increase with the expanding global production of sequences across a variety of laboratories...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to SARS-CoV-2 and COVID-19 Research
Share to SARS-CoV-2 detection and testing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34907347
DOI: 10.1038/s41564-021-01019-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synthetic DNA spike-ins (SDSIs) enable sample tracking and detection of inter-sample contamination in SARS-CoV-2 sequencing workflowsPMID 34907347Read ↗

DNA spike-ins enable confident interpretation of SARS-CoV-2 genomic data from amplicon-based sequencingSemantic proximity Read ↗

Targeted Amplification and Genetic Sequencing of the Severe Acute Respiratory Syndrome Coronavirus 2 Surface GlycoproteinSemantic proximity Read ↗

<i>In silico</i> analyses identifies sequence contamination thresholds for Nanopore-generated SARS-CoV2 sequencesSemantic proximity Read ↗

One-Seq: A Highly Scalable Sequencing-Based Diagnostic for SARS-CoV-2 and Other Single-Stranded VirusesSemantic proximity Read ↗

Recommendations for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samplesSemantic proximity Read ↗

ConSeqUMI, an error-free nanopore sequencing pipeline to identify and extract individual nucleic acid molecules from heterogeneous samplesSemantic proximity Read ↗

External Quality Assessment of SARS-CoV-2 Sequencing: an ESGMD-SSM Pilot Trial across 15 European LaboratoriesSemantic proximity Read ↗

High-Integrity Sequencing of Spike Gene for SARS-CoV-2 Variant Determination.Semantic proximity Read ↗

Bioinformatic investigation of discordant sequence data for SARS-CoV-2: insights for robust genomic analysis during pandemic surveillanceSemantic proximity Read ↗

Optimized quantification of intra-host viral diversity in SARS-CoV-2 and influenza virus sequence data.Semantic proximity Read ↗

Optimized Quantification of Intrahost Viral Diversity in SARS-CoV-2 and Influenza Virus Sequence DataSemantic proximity Read ↗

Analysis of the ARTIC Version 3 and Version 4 SARS-CoV-2 Primers and Their Impact on the Detection of the G142D Amino Acid Substitution in the Spike Protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.