Article
Long-term mutation rates in the hepatitis B virus genome.
The Journal of general virology - 1 Jan 2000
Hannoun C, Horal P, Lindh M
Abstract excerpt
Mutations in the hepatitis B virus (HBV) genome have so far been investigated in cross-sectional or short-term longitudinal studies. Information about long-term changes is lacking due to the difficulty of sampling over long observation periods. In this study, a retrospective approach was used that allowed the analysis of changes in the viral genome from transmission to late stages of infection without the...
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