Article
Hepatitis B virus genetic mutations and evolution in liver diseases.
World journal of gastroenterology - 14 May 2014
Shen Tao, Yan Xin-Min
Abstract excerpt
Hepatitis B virus (HBV) belongs to the genus Orthohepadnavirus of the Hepadnaviridae family and is approximately 3.2 kb in length. Owing to a lack of proofreading capacity during reverse transcription and a high replication rate, HBV exhibits as quasispecies. To detect the genetic mutations of HBV, many methods with different sensitivities and throughputs were developed. According to documentary records, HBV...
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