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Article

FAAH polymorphism (rs324420) modulates extinction recall in healthy humans: an fMRI study.

European archives of psychiatry and clinical neuroscience - 1 Dec 2022

Spohrs Jennifer, Ulrich Martin, Grön Georg, Plener Paul L, Abler Birgit

Abstract excerpt

Gold standard treatments for anxiety- and trauma-related disorders focus on exposure therapy promoting extinction learning and extinction retention. However, its efficacy is limited. Preclinical and particularly animal research has been able to demonstrate that homozygosity for the fatty acid amide hydrolase (FAAH) C385A allele, similar to FAAH inhibition, is associated with elevated concentrations of anandamide...

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Identifiers

PMID: 34893921
DOI: 10.1007/s00406-021-01367-4
PMCID: PMC9653364

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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