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Article

The combined effects of nucleotide-binding domain-like receptor protein 3 polymorphisms and levels of blood lead on developmental delays in preschool children.

Journal of hazardous materials - 15 Feb 2022

Hsueh Yu-Mei, Chen Wei-Jen, Chung Chi-Jung, Hsieh Ru-Lan, Chen Hsi-Hsien, Huang Ya-Li, Shiue Horng-Sheng, Lin Ming-I, Mu Shu-Chi, Lin Ying-Chin

Abstract excerpt

Nucleotide-binding domain-like receptors protein 3 (NLRP3) inflammasomes are associated with neuroinflammation and multiple NLRP3 genes regulate NLRP3 expression. Our study aimed to investigate the association of NLRP3 polymorphisms with developmental delay in preschool children. We also explored whether NLRP3 polymorphisms modified the effects of total urinary arsenic and blood cadmium and lead to developmental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34879550
DOI: 10.1016/j.jhazmat.2021.127317

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