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Intrauterine chromium exposure and cognitive developmental delay: The modifying effect of genetic predisposition.

The Science of the total environment - 10 Oct 2024

Jia Zhenxian, Zhang Hongling, Lv Yiqing, Yu Ling, Cui Yuan, Zhang Liping, Yang Chenhui, Liu Hongxiu, Zheng Tongzhang, Xia Wei, Xu Shunqing, Li Yuanyuan

Abstract excerpt

There is limited evidence on the effects of intrauterine chromium (Cr) exposure on children's cognitive developmental delay (CDD). Further, little is known about the genetic factors in modifying the association between intrauterine Cr exposure and CDD. The present study involved 2361 mother-child pairs, in which maternal plasma Cr concentrations were assessed, a polygenic risk score for the child was constructed,...

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Identifiers

PMID: 38960203
DOI: 10.1016/j.scitotenv.2024.174350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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