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Article

Polymorphism of nucleotide binding domain-like receptor protein 3 (NLRP3) increases susceptibility of total urinary arsenic to renal cell carcinoma.

Scientific reports - 20 Apr 2020

Chung Chi-Jung, Bao Bo-Ying, Lin Ying-Chin, Huang Ya-Li, Shiue Horng-Sheng, Ao Pui-Lam, Pu Yeong-Shiau, Huang Chao-Yuan, Hsueh Yu-Mei

Abstract excerpt

Our study showed that total urinary arsenic concentrations were positively correlated with renal cell carcinoma (RCC). Chronic inflammation is a key player in the development of RCC. This study explored the association between nucleotide-binding domain-like receptor protein 3 (NLRP3) genotypes and the development of RCC. We also investigated whether any of the NLRP3 genotypes modified the risk between arsenic and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32313131
DOI: 10.1038/s41598-020-63469-8
PMCID: PMC7171170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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