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Article

A function of CBP as a transcriptional co-activator during Dpp signalling.

The EMBO journal - 15 Mar 1999

Waltzer L, Bienz M

Abstract excerpt

CBP/p300 is a transcriptional co-activator that is recruited to enhancers by various DNA-binding proteins, including proteins whose activity is controlled by extracellular signals. Here, we report that Drosophila CBP loss-of-function mutants show specific defects which mimic those seen in mutants that lack the extracellular signal Dpp or its effector Mad. Furthermore, we find that CBP loss severely compromises...

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Identifiers

PMID: 10075933
DOI: 10.1093/emboj/18.6.1630
PMCID: PMC1171250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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