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Genetic contributions to female gout and hyperuricaemia using genome-wide association study and polygenic risk score analyses.

Rheumatology (Oxford, England) - 1 Feb 2023

Lin Chien-Yu, Chang Ya-Sian, Liu Ting-Yuan, Huang Chung-Ming, Chung Chin-Chun, Chen Yu-Chia, Tsai Fuu-Jen, Chang Jan-Gowth, Chang Shun-Jen

Abstract excerpt

OBJECTIVES: To identify genetic variants and polygenic risk score (PRS) relating to female gout and asymptomatic hyperuricaemia (AH) in a genome-wide association study (GWAS). METHODS: Gout, AH and normouricemia controls were included from Taiwan biobank and China Medical University Hospital. All participants were divided into discovery and replication cohorts for GWAS. PRS was estimated according to whether the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35758599
DOI: 10.1093/rheumatology/keac369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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