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Synergistic effects of female-specific conditions and genetic risk on cardiometabolic disease: a cohort study.

Heart (British Cardiac Society) - 11 Sept 2025

Yin Jiayu, Li Tingting, Yu Zongliang, Yu Lingchan, Bian Liyan, Xiang Boyang, Gu Xiaosong

Abstract excerpt

BACKGROUND: The role of female-specific factors in the occurrence and progression of cardiometabolic disease (CMD) across different genetic risks remains incompletely clear. This study aimed to comprehensively assess the association of female-specific factors with the occurrence and progression of CMD. METHODS: This was a prospective cohort study of 150 413 female individuals from the UK Biobank. The...

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PMID: 40139682
DOI: 10.1136/heartjnl-2024-325355

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