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Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer

19 Oct 2020

Abstract excerpt

Abstract We present a study to evaluate the feasibility and clinical utility of amplicon‐based Oncomine Pan‐Cancer cell‐free assay to detect circulating tumor DNA (ctDNA) in patients with early or advanced breast cancer. In this study, 109 early and metastatic breast cancer patients were recruited before the initiation of treatment. ctDNA mutation profiles were assessed through unique molecular tagging (UMT) and...

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PMID: 33075187
DOI: 10.1111/cas.14697

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