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Article

Functional and structural phenotyping of cardiomyocytes in the 3D organization of embryoid bodies exposed to arsenic trioxide.

Scientific reports - 30 Nov 2021

Rebuzzini Paola, Civello Cinzia, Fassina Lorenzo, Zuccotti Maurizio, Garagna Silvia

Abstract excerpt

Chronic exposure to environmental pollutants threatens human health. Arsenic, a world-wide diffused toxicant, is associated to cardiac pathology in the adult and to congenital heart defects in the foetus. Poorly known are its effects on perinatal cardiomyocytes. Here, bioinformatic image-analysis tools were coupled with cellular and molecular analyses to obtain functional and structural quantitative metrics of...

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Identifiers

PMID: 34848780
DOI: 10.1038/s41598-021-02590-8
PMCID: PMC8633008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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