Article
Genetic diversity and population structure of the human malaria parasite Plasmodium falciparum surface protein Pfs47 in isolates from the lowlands in Western Kenya.
PloS one - 1 Jan 2021
Onyango Shirley A, Ochwedo Kevin O, Machani Maxwell G, Omondi Collince J, Debrah Isaiah, Ogolla Sidney O, Lee Ming-Chieh, Zhou Guofa, Kokwaro Elizabeth, Kazura James W, Afrane Yaw A, Githeko Andrew K, Zhong Daibin, Yan Guiyun
Abstract excerpt
Plasmodium falciparum parasites have evolved genetic adaptations to overcome immune responses mounted by diverse Anopheles vectors hindering malaria control efforts. Plasmodium falciparum surface protein Pfs47 is critical in the parasite's survival by manipulating the vector's immune system hence a promising target for blocking transmission in the mosquito. This study aimed to examine the genetic diversity,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.