Article
Plasmodium falciparum Genetic Diversity in Coincident Human and Mosquito Hosts.
mBio - 26 Oct 2022
Lapp Zena, Obala Andrew A, Abel Lucy, Rasmussen David A, Sumner Kelsey M, Freedman Elizabeth, Taylor Steve M, Prudhomme-O'Meara Wendy
Abstract excerpt
Population genetic diversity of Plasmodium falciparum antigenic loci is high despite large bottlenecks in population size during the parasite life cycle. The prevalence of genetically distinct haplotypes at these loci, while well characterized in humans, has not been thoroughly compared between human and mosquito hosts. We assessed parasite haplotype prevalence, diversity, and evenness using human and mosquito P....
Topics
- Animals
- Humans
- Culicidae
- Genetic Variation
- Longitudinal Studies
- Malaria, Falciparum
- Plasmodium falciparum