Article
The Organization of Pericentromeric Heterochromatin in Polytene Chromosome 3 of the Drosophilamelanogaster Line with the Rif11; SuURES Su(var)3-906 Mutations Suppressing Underreplication.
Cells - 20 Oct 2021
Zykova Tatyana, Maltseva Mariya, Goncharov Fedor, Boldyreva Lidia, Pokholkova Galina, Kolesnikova Tatyana, Zhimulev Igor
Abstract excerpt
Although heterochromatin makes up 40% of the Drosophila melanogaster genome, its organization remains little explored, especially in polytene chromosomes, as it is virtually not represented in them due to underreplication. Two all-new approaches were used in this work: (i) with the use of a newly synthesized Drosophila line that carries three mutations, Rif11, SuURES and Su(var)3-906, suppressing the...
Topics
- Animals
- Antibodies
- Carrier Proteins
- Chromosomal Proteins, Non-Histone
- DNA Replication
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Genes, Essential
- Genome, Insect
- Guanine Nucleotide Exchange Factors
- Heterochromatin