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Article

Epigenetics and immune cells in medulloblastoma

10 Mar 2023

Abstract excerpt

Medulloblastoma (MB) is a highly malignant childhood tumor of the cerebellum. Transcriptional and epigenetic signatures have classified MB into four molecular subgroups, further stratified into biologically different subtypes with distinct somatic copy-number aberrations, driver genes, epigenetic alterations, activated pathways, and clinical outcomes. The brain tumor microenvironment (BTME) is of importance to...

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PMID: 36968588
DOI: 10.3389/fgene.2023.1135404

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